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Katherine P Ponder Selected Research

Mucopolysaccharidosis VII (Sly Syndrome)

2/2016Evaluation of AAV-mediated Gene Therapy for Central Nervous System Disease in Canine Mucopolysaccharidosis VII.
11/2013The effect of neonatal gene therapy with a gamma retroviral vector on cardiac valve disease in mucopolysaccharidosis VII dogs after a decade.
11/2013Pathogenesis of mitral valve disease in mucopolysaccharidosis VII dogs.
9/2012Pathogenesis of lumbar spine disease in mucopolysaccharidosis VII.
9/2012Effect of neonatal gene therapy on lumbar spine disease in mucopolysaccharidosis VII dogs.
12/2011Pathogenesis of aortic dilatation in mucopolysaccharidosis VII mice may involve complement activation.
5/2010Altered lumbar spine structure, biochemistry, and biomechanical properties in a canine model of mucopolysaccharidosis type VII.
7/2009Mechanism of shortened bones in mucopolysaccharidosis VII.

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Katherine P Ponder Research Topics

Disease

15Mucopolysaccharidosis I (Hurler Syndrome)
12/2014 - 07/2006
10Lysosomal Storage Diseases (Lysosomal Storage Disease)
02/2016 - 01/2008
8Mucopolysaccharidosis VII (Sly Syndrome)
02/2016 - 07/2009
7Mucopolysaccharidoses
02/2015 - 09/2007
2Disease Progression
12/2014 - 12/2011
2Aortic Diseases
04/2010 - 07/2008
2Hemophilia B (Haemophilia B)
01/2007 - 09/2006
2Hemophilia A (Haemophilia)
09/2006 - 04/2005
1Mitral Valve Insufficiency (Mitral Regurgitation)
11/2013
1Bone Diseases (Bone Disease)
05/2012
1Hypertrophy
12/2011
1Heart Failure
06/2011
1Spinal Cord Compression
10/2010
1Neoplasms (Cancer)
11/2008
1Cardiovascular Diseases (Cardiovascular Disease)
07/2008
1Heart Diseases (Heart Disease)
01/2008
1Protein Deficiency
10/2006
1Hemorrhage
04/2005

Drug/Important Bio-Agent (IBA)

23GlycosaminoglycansIBA
02/2016 - 02/2007
15Iduronidase (alpha-L-Iduronidase)IBA
12/2014 - 07/2006
12GlucuronidaseIBA
02/2016 - 11/2008
8EnzymesIBA
02/2015 - 09/2007
3Proteins (Proteins, Gene)FDA Link
05/2012 - 07/2008
2ChondroitinIBA
09/2012 - 09/2012
2Dermatan SulfateIBA
09/2012 - 09/2012
2Pancreatic Elastase (Elastase)IBA
04/2010 - 07/2008
2Factor IX (Coagulation Factor IX)FDA LinkGeneric
01/2007 - 09/2006
2Factor VIII (Coagulation Factor VIII)IBA
09/2006 - 04/2005
1Simvastatin (Zocor)FDA LinkGeneric
12/2014
1CollagenIBA
11/2013
1Heparitin Sulfate (Heparan Sulfate)IBA
07/2013
1N-Acetylgalactosamine-4-Sulfatase (Arylsulfatase B)IBA
05/2012
1SulfatasesIBA
05/2012
1CytokinesIBA
04/2010
1DNA (Deoxyribonucleic Acid)IBA
11/2008
1cathepsin SIBA
07/2008
1ElastinIBA
07/2008
1Messenger RNA (mRNA)IBA
07/2008
1Mannose (D-Mannose)IBA
01/2008
1Complement System Proteins (Complement)IBA
10/2006
1Abatacept (Orencia)FDA Link
07/2006
1AntibodiesIBA
04/2005
1Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric
04/2005

Therapy/Procedure

5Enzyme Replacement Therapy
12/2014 - 01/2008
3Therapeutics
12/2011 - 04/2005
3Intravenous Injections
11/2008 - 01/2008
1Hematopoietic Stem Cell Transplantation
12/2011
1Immunomodulation
05/2007